Genomics

Often, the term genetics and genomics are used interchangeably. "Genetics" might be a term with which you are more familiar. In terms of disease, genetics usually refers to single gene disorders such a cystic fibrosis or Down syndrome. Although these conditions are of great importance to individuals and families with them, they are relatively rare and most people are not directly affected.

The term "genomics" combines both the traditional roles of genetics and new evidence from the Human Genome Project (HGP), that genes interact with environmental factors to predispose some persons to common diseases such as colon cancer, diabetes, and arteriosclerosis. Experts believe that information from the HGP will be used to prevent disease and improve health among virtually all patients.

AAPA Policy

Genetic Testing in Clinical Practice policy paper
Guidelines for Ethical Conduct for the Physician Assistant Profession

Genetic Testing

Evaluating the risk of disease and performing diagnostic genetic tests raise significant ethical concerns. Physician assistants should be informed about the benefits and risks of genetic tests. Testing should be undertaken only after proper informed consent is obtained. If PAs order or conduct the tests, they should assure that appropriate pre- and post-test counseling is provided.

PAs should be sure that patients understand the potential consequences of undergoing genetic tests − from impact on patients themselves, possible implications for other family members, and potential use of the information by insurance companies or others who might have access to the information. Because of the potential for discrimination by insurers, employers, or others, PAs should be particularly aware of the need for confidentiality concerning genetic test results.